June 5th, 2013

flasks

People who need to be stabbed with sporks.

You know what makes me really fuckin' angry? People who boast that they don't take any medications that are made in a lab. As I said to one of these loons today, you have no idea how lucky you are to have the CHOICE not to take prescription drugs. I personally have the choice of taking prescription drugs or dying.

I was explaining to some people who don't know me well about the delights of chronotherapy, and why today I got up at 2 am and will remain up until at least 2 pm. And said people were trying to convince me that I should try drinking alcohol or smoking pot for my sleep problems. Because, yeah, that's a bloody great idea for someone on several medications which say not to mix it with alcohol, and who as a result of chronic fatigue syndrome has no tolerance for it at all (as in a few sips of something alcoholic puts me under the table and feeling awful). And who is extremely asthmatic and starts retching and puking when even vaguely near pot smoke.

Oh yeah, and apparently "weed won't cause variable effects with other medications". I'm on carbamazepine, which is a cytochrome P450 inducer, and that is affected by somewhere between half and two-thirds of all other medications, including natural remedies. The chemicals in pot, of which there are many, could make me need to increase or decrease the dosage of any or all of my meds. If I could find academic papers stating which particular biochemical pathways are affected by it, then I might consider it. But the fact it's illegal means there is insufficient information about drug interactions. The other problem with it being illegal is you can never be certain what dose you're getting. I prefer drugs where the dosage is known.

*stab stab stab*

In other news, I have a new wheelchair. It's a new-to-me wheelchair rather than new. It was made in 1998. However, it is built like a fricking TANK. It is higher off the ground than my old one, "for a more important appearance on the road"(*) and also very, very red. I'll link you to the eBay auction for now because I lack spoons to take my own photos. There's also more pictures in this brochure, although mine doesn't have the riser or tilt functions, not least of all because I don't need them.

(*) Engrish phrase from the Di Biasi tricycle catalogue, circa 5 years ago.
gaming

Random links

It's Wednesday, and I have actually READ BOOKS THIS WEEK (!). So I should do that Wednesday reading meme thing. Unfortunately I'm exhausted and have lost coherence, AND still have another 2 hours before I can go to bed. Gods damnit.

So have some links that have been sitting in my browser for weeks:

people say I'm gonna regret this, I say fuck you. A Reddit thread in which a user boasts about his tattoo of an illegal drug... which turns out to be so not the molecule he thought it was that it would make anyone with A-level chemistry laugh their arses off. Mmm. Yeah. Benzene rings are tricky little buggers, aren't they?

On similar lines (perhaps), A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine. "In recent years it has become increasingly difficult to obtain psuedoephedrine in many states because of its use as a precursor for the illegal drug N-methylamphetamine (also known under various names including crystal meth, meth, ice, etc.)" "A quick search of several neighborhoods of the United States revealed that while pseudoephedrine is difficult to obtain, N-methylamphetamine can be procured at almost any time on short notice and in quantities sufficient for synthesis of useful amounts of the desired material." Given that it's published in the Journal of Apocryphal Chemistry, somehow I doubt this is real... But any organic synthesis route can be reversed, so... I dunno. I laughed anyway.

Groovy glasses. "Ok let's see if that thing with glasses chicks suddenly becoming super weird feminine when they whip off their glasses works". You kinda have to go all the way to the end to find the really funny pictures.

Introducing 'SheZow,' The 'Transgender' Superhero Cartoon That Will Destroy America And/Or Entertain Some Children. I liked this review. Haven't bothered watching any of the cartoon clips though.

How I Lost Faith in the “Pro-Life” Movement. I have a vague feeling I may have linked to this before, but it's worth reading if you have enough spare time to read the whole, very long, article, and are not already in a stabby mood.